Pagani is a surname. Notable people with the name include:
Alberto Pagani (1938–2017), Italian Grand Prix motorcycle road racer Alessandro Pagani (born 1937), Italian Roman Catholic bishop Alfredo Pagani (1887–1984), Italian athlete Angelo Pagani (born 1988), Italian cyclist Daniele Pagani (born 1966), Italian high jumper Fabrizio Pagani (born 1967), Italian economist Gregorio Pagani (1558–1605), Italian painter of the late Mannerist period Herbert Pagani (1944–1988), Italian artist and musician Horacio Pagani (auto executive) (born 1955), Argentine founder of Pagani Automobili S.p.A. Horacio Pagani (sportswriter) (born 1948), Argentine sportswriter and sportscaster Lattanzio Pagani, Italian painter of the late-Renaissance or Mannerist period Maghinardo Pagani, Italian condottiero and statesman Marcelo Pagani (born 1941), Argentine footballer Maurizio Pagani (1936–2014), Italian engineer and politician Mauro Pagani (born 1946), Italian musician and singer Nello Pagani (1911–2003), Italian Grand Prix motorcycle road racer and Formula One driver Nicola Pagani (born 1977), Italian footballer Paolo Pagani (1655–1716), Italian Baroque/Mannerism painter Rémy Pagani (born 1954), Swiss politician Vincenzo Pagani (c. 1490–1568), Italian painter