Guillemette may refer to:
People Alphonse-Edgar Guillemette (1877–1950), Canadian politician Éloi Guillemette (1911–1984), Canadian politician Hélène Guillemette, Canadian politician Joanne Guillemette, U.S. politician Nancy Guillemette, Canadian politician Guillemette Andreu (born 1948), French Egyptologist and archaeologist Guillemette du Luys (fl. 1479), French surgeon Guillemette Laurens (born 1957), French opera singer Guillemette of Neufchâtel (1260–1317), French noblewoman Guillemette de Sarrebruck (1490–1571), French court official
See also Guillemet, a punctuation mark