Aisi or AISI may refer to:
Organizations African Information Society Initiative of UNECA Agenzia Informazioni e Sicurezza Interna, the internal intelligence agency of Italy Alberta Initiative for School Improvement, Canada American Iron and Steel Institute, an American trade organization Artificial intelligence safety institute, a type of research body AI Security Institute, a British government body
Other uses Aisi language, Papua New Guinea Hazaaron Khwaishein Aisi, 2003 Indian film Robert Guba Aisi, Papua New Guinean diplomat