XDS could refer to:
Cross Enterprise Document Sharing, a system for sharing clinical documents between healthcare institutions Direct Save Protocol, a feature of the X Window System graphical user interface for Unix-like computer operating systems Envoy discovery services, see Extended Data Services, a US standard for TV metadata transmission External Development Summit, an event for the video game industry Ottawa station, train station in Ottawa, Ontario, Canada with IATA code XDS used by Air France–KLM's connecting bus service Springfield Armory XD-S, a pistol sold in the United States designed for concealed carry X-ray diffuse scattering, a materials analysis technique X-Digital Systems satellite subcarrier audio format Xerox Data Systems, the name for Scientific Data Systems after it was purchased by Xerox Corporation