Doe is a surname. Notable people with the surname include:

Brian Doe (1862–1941), Australian politician Charles Doe (1898–1995), American rugby union player. David Doe (born 2000), Canadian soccer player Donald Brian Doe (1920–2005), British archaeologist and architect Edward M. Doe (1850–1919), American jurist Francis Doe (born 1985), Liberian footballer Fred Doe (1864–1938), American baseball pitcher Janet Doe (1895–1985), medical librarian John Doe or Jane Doe, a name used as a placeholder for an unknown or anonymous person, especially in a legal context Joseph Doe (1855–1925), American military officer, politician and baseball player Lindsey Doe (born 1981/1982), sexologist and sex educator Michael Doe (businessman) (died 1990), British-Liberian businessman Michael Doe (bishop) (born 1947), British bishop Nancy Doe (1949–2025), First Lady of Liberia, wife of Samuel Nicholas B. Doe (1786–1856), American politician Samuel Doe (1951–1990), leader of Liberia (1980–1990) Samuel Gbaydee Doe (born 1966), peacebuilding and conflict analyst from Liberia Thomas Doe (1912–1969), American bobsledder William Doe (1941–2022), Australian professor