Wisner is a surname. Notable people with the surname include:
Frank Wisner (1910–1965), American civil servant and father of Frank G. Wisner Frank G. Wisner (1938–2025), American diplomat and son of Frank Wisner Henry Wisner (c. 1720–1790), American politician Moses Wisner (1815–1863), American politician Quintrevion Wisner (born 2005), American football player