Middletown School District can refer to the following public school districts in the United States:
Enlarged City School District of Middletown in Middletown, New York Middletown Area School District in Middletown, Pennsylvania Middletown City School District in Middletown, Ohio Middletown Township Public School District in Middletown Township, New Jersey Middletown Unified School District in Lake County, California Middletown Public Schools (Rhode Island)
See also Middleton School District, Idaho Appoquinimink School District, which serves Middletown, Delaware