Ogunlesi is a surname. Notable people with the surname include:
Adebayo Ogunlesi (born 1953), Nigerian lawyer and investment banker Mowalola Ogunlesi (born 1955), Nigerian-born fashion designer Tanimowo Ogunlesi (1908–2002), Nigerian women's rights activist Tolu Ogunlesi (born 1982), Nigerian journalist, poet, photographer, and writer