Mystery Girl is an album by Roy Orbison.

Mystery Girl(s) or The Mystery Girl may also refer to:

Film and television The Mystery Girl, a lost 1918 American silent film directed by William C. deMille Mystery Girl (The Naked Brothers Band), a 2008 television film featuring the Naked Brothers Band Mystery Girls, a 2014 American television sitcom

Music "Mystery Girl" (song), by Alexandra Savior, 2016 "Mystery Girl", a song by Atlantic Starr from Radiant, 1981 "Mystery Girl", a song by Brad Whitford and Derek St. Holmes from Whitford/St. Holmes, 1981 "Mystery Girl", a song by Jess Conrad, 1961 "Mystery Girl", a song by Yeah Yeah Yeahs from Yeah Yeah Yeahs, 2001 The pseudonym for Princess Stéphanie of Monaco on the Michael Jackson song "In the Closet" featuring her

See also His Mystery Girl, a 1923 American silent film directed by Robert F. Hill