Culhane is a surname. Notable people with the surname include:
Jim Culhane (born 1965), Canadian ice hockey player John Culhane (1900–1979), Australian footballer Kathleen Culhane Lathbury (1900–1993), British biochemist Kieran Culhane, Irish footballer Leonard Culhane (born 1937), British astronomer Noreen Culhane (born 1950), American businesswoman Shamus Culhane (1908–1996), American animator, film director and producer Simon Culhane (born 1968), New Zealand rugby player