C65 or C-65 may refer to: Autovía C-65, a road in Catalonia, Spain Berlin Defence (chess), a chess opening Caldwell 65, a spiral galaxy Caudron C.65, a French biplane Commodore 65, a prototype home computer Honda Super Cub, a motorcycle Siemens C65, a mobile phone Stout XC-65, an American experimental aircraft C65, a racing car chassis from Courage Compétition