Mayapa–Canlubang Cadre Road, also known as Mayapa Road, is a two- to four-lane, secondary national road, located in Calamba, Laguna in the Philippines. It spans stretching from the "Checkpoint" area at the intersection with Manila South Road in barangay Paciano Rizal to Jose Yulo Sr. Avenue and Silangan Industrial Park Road (Doña Cecila Yulo Avenue) in barangay Canlubang. This road adjoins the Canlubang Exit of South Luzon Expressway.
In 2015, the road was reclassified from barangay road to tertiary national road. In 2025, it was reclassified as a secondary national road, thus becoming National Route 420-1 (N420-1) of the Philippine highway network.
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