C60, C.60, or C-60 may refer to:

Vehicles and transport Caudron C.60, a 1920s French two-seat biplane Chevrolet C-60, a medium-duty truck Lockheed C-60 Lodestar a WW2-era transport airplane JNR Class C60, a Japanese class of steam locomotives Autovia C-60, a highway in Catalonia, Spain

Science Buckminsterfullerene, a carbon molecule with the chemical formula C60, also known as a buckyball Caldwell 60, one of the Antennae Galaxies in the constellation Corvus Corydoras osteocarus, a freshwater catfish Carcinoma of the penis ICD-10 code A kind of carbon called carbon fibre

Other uses AMD C-60 (formerly AMD Fusion C-60), a computer processor by AMD, codename "Ontario" Bill C-60, a proposed Canadian law C60 (band), a band also known as Cobalt 60 A 60-minute audio Compact Cassette tape Ruy Lopez chess openings ECO code