Mokoena is a South African surname. Notable people by that name include:
Aaron Mokoena (born 1980), South African international footballer Fana Mokoena (born 1971), South African actor Godfrey Khotso Mokoena (born 1985), South African athlete Julian Mokoena, South African politician Nthabiseng Mokoena, South African intersex activist Teboho Mokoena (born 1974), South African former international footballer Teboho Mokoena (born 1997), South African international footballer Thapelo Mokoena, South African actor Thabang Mokoena, (born 2006), South African international footballer
See also The River (South African TV series), The Mokoena family, consisting of Malefu Mokoena and her children, Thuso, Dimpho and Itumeleng, live in Refilwe.