Pfeiffera is a genus of flowering plants in the family Cactaceae, found in Bolivia and northwest Argentina. There has been some debate about the circumscription of the genus. It is placed in the tribe Echinocereeae.

The genus name of Pfeiffera is in honour of Ludwig Karl Georg Pfeiffer (1805–1877), a German physician, botanist and conchologist. It was first described and published in Cact. Hort. Dyck., edt. 1844 on page 40 in 1845.

Species The following species are accepted: Image Scientific name Distribution Pfeiffera asuntapatensis (M.Kessler, Ibisch & Barthlott) Ralf Bauer Bolivia Pfeiffera boliviana (Britton) D.R.HuntBolivia. Pfeiffera ianthothele F.A.C.Weber Bolivia to NW. Argentina Pfeiffera miyagawae Barthlott & RauhBolivia. Pfeiffera monacantha (Griseb.) P.V.HeathBolivia to NW. Argentina Pfeiffera paranganiensis (Cárdenas) P.V.HeathBolivia

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