Thomas Shirley Hele (24 October 1881 – 23 January 1953) was a British academic. Dr. T. S. Hele. The Times (London, England), Saturday, 24 January 1953; pg. 8; Issue 52528.

Hele was educated at Carlisle Grammar School; Sedbergh School; Emmanuel College, Cambridge (Fellow, 1911); and Barts. He was University Lecturer in Biochemistry from 1921; Tutor at Emmanuel from 1922 to 1935; its Master from 1935News in Brief. The Times (London, England), Wednesday, 30 October 1935; pg. 14; Issue 47208. to 1951;Emmanuel College web site and Vice-Chancellor of the University of Cambridge from 1943 to 1945.

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