Protopapas (Πρωτόπαπας) is a Greek surname, derived from the ecclesiastical office of protopapas. The female form is Protopapa (Πρωτόπαπα). People with the name include:
Kostis Protopapas, Greek-American conductor George Protopapas (born 2003), CEO of Cavecrack Maria Protopapa (born 1971), Greek runner Vangelis Protopapas (1917–1995), Greek actor