Wikramanayake is a surname. Notable people with the surname include:
Arittha R Wikramanayake, Sri Lankan lawyer Athula Wikramanayake, Sri Lankan American developmental biologist Elanga Wikramanayake, Sri Lankan lawyer Eric Bird Wikramanayake, Ceylonese statesman and lawyer, Minister of Justice Eric Wikramanayake, Sri Lankan conservationist Gihan Wikramanayake (1960-2018), Sri Lankan academic Jayathma Wickramanayake (born 1990), Sri Lankan activist and UN Special Envoy on Youth V. S. de S. Wikramanayake (1876-1952), Sri Lankan politician