Stamos is a surname of Greek origin. Notable people with the surname include:
Alex Stamos (born 1979), American computer scientist David N. Stamos (born 1957), Canadian philosopher and professor John Stamos (born 1963), American actor, producer, musician, and singer John J. Stamos (1924–2017), Greek-American Justice of the Supreme Court of Illinois Theodoros Stamos (1922–1997), Greek-American painter