Merchants Bank Building may refer to:
Merchants Bank Building (Daytona Beach, Florida), also known as the Halifax Historical Museum, listed on the National Register of Historic Places (NRHP) Merchants Bank Building (Providence, Rhode Island), NRHP-listed Merchant Bank Building (Kharkiv), historical building in Kharkiv, Ukraine
See also Merchants and Farmers Bank Building, Okolona, Mississippi, NRHP-listed Merchants and Planters Bank (Clarendon, Arkansas), NRHP-listed