Benincasa is an Italian surname. Notable people with the surname include:

Carmine Benincasa (1947–2020), Italian art critic and art historian professor Caterina Benincasa or Catherine of Siena (1347–1380), tertiary of the Dominican Order and a Scholastic philosopher and theologian Pius Anthony Benincasa (1913–1986), bishop of the Catholic Church in the United States Sara Benincasa (born 1980), American comedian and author

See also Benincasa da Montepulciano (1375–1426), Italian Roman Catholic professed religious from the Servite Order