Chandrasekharan is a South-Indian first name and surname. Notable people include:
E. Chandrasekharan (born 1948), Indian politician Guru Chandrasekharan (1916–1998), Indian dancer and choreographer K. S. Chandrasekharan (1920–2017), Indian number theorist Kottakkal Chandrasekharan, Indian dancer M. R. Chandrasekharan (1929–2024), Indian literary critic and author Salem Chandrasekharan, Indian film producer T. P. Chandrasekharan (1960–2012), Indian politician Natarajan Chandrasekaran (born 1963), chairman of Tata Sons