Amsler is a surname. Notable people with the surname include:
Guy Amsler (1895–1986), associate justice of the Arkansas Supreme Court Marc Amsler (1891–1968), Swiss ophthalmologist Amsler grid Amsler sign, a medical sign Margaret Harris Amsler (1908–2002), American lawyer and academic Marty Amsler (1942–2024), American football player Samuel Amsler (1791–1849), Swiss engraver
See also Jakob Amsler-Laffon (1823–1912), Swiss mathematician, physicist and engineer Amsler Island, an island of the Palmer Archipelago, Antarctica