Mailer is a surname. Notable people with the surname include:

John Buffalo Mailer (born 1978), author, playwright and journalist Kate Mailer (born 1962), American stage and film actress Michael Mailer (born 1964), film producer Norman Mailer (1923–2007), American novelist, journalist, essayist, poet, playwright, screenwriter, and film director Ron Mailer (1932–2018), Scottish footballer Susan Mailer (born 1949), American psychoanalyst Stephen Mailer (born 1966), American stage and screen actor

See also Lee B. Mailler (1898–1967), New York politician