Sacconi is an Italian surname. Notable people with the surname include:
Antonio Sacconi (1895–1968), Italian chess master Carlo Sacconi (1808–1889), Cardinal of the Roman Catholic Church and Dean of the College of Cardinals Deyvid Sacconi (born 1987), Brazilian footballer Giuseppe Sacconi (1854-1905), Italian architect Guido Sacconi (1948–2023), Italian politician Maurizio Sacconi (born 1950), Italian politician Simone Fernando Sacconi (1895–1973), Italian violin maker and restorer
Other Sacconi Quartet, UK-based classical music string quartet founded in 2001