Guirao is a surname. Notable people with the surname include:
Carlos Guirao (footballer) (born 2003), Spanish footballer Carlos Guirao (musician) (1954–2012), Spanish musician José Guirao (1959–2022), Spanish cultural manager, art expert and former minister of culture Miguel Guirao (born 1996), Spanish footballer Olga Guirao (born 1956), Spanish novelist Rodrigo Guirao Díaz (born 1980), Argentine actor