Kyriazis () is a Greek surname. Notable people with the surname include:

Chrysanthos Kyriazis (born 1972), Greek volleyball player Damianos Kyriazis (1890–1948), Greek politician and philanthropist Georgios Kyriazis (born 1980), Greek footballer Ilias Kyriazis (born 1978), Greek comics artist Marios Kyriazis (born 1956), British/Greek Cypriot physician Neoklis Kyriazis (1877–1956), Greek Cypriot historian