The International System for Human Cytogenomic Nomenclature (ISCN; previously the International System for Human Cytogenetic Nomenclature) is an international standard for human chromosome nomenclature, which includes band names, symbols, and abbreviated terms used in the description of human chromosome and chromosome abnormalities.
The ISCN has been used as the central reference among cytogeneticists since 1960.Slovak M.L., Theisen A., Shaffer L.G. (2013) "Human Chromosome Nomenclature: An Overview and Definition of Terms." In: Gersen S., Keagle M. (eds) The Principles of Clinical Cytogenetics. Springer, New York, NY
Abbreviations of this system include a minus sign (-) for chromosome deletions, and del for deletions of parts of a chromosome.
Revision history ISCN (2024). S. Karger Publishing. . Also published as Cytogenet Genome Res 2024;164(suppl 1):1–224, doi:10.1159/000538512 . ISCN (2020). S. Karger Publishing. ISCN (2016). S. Karger Publishing. ISCN (2013). S. Karger Publishing. ISCN (2009). S. Karger Publishing. ISCN (2005). S. Karger Publishing. ISCN (1995). S. Karger Publishing. ISCN (1991). S. Karger Publishing. ISCN (1985). S. Karger Publishing. ISCN (1981). S. Karger Publishing. ISCN (1978). S. Karger Publishing. Paris Conference (1971): "Standardization in Human Cytogenetics." (PDF) Birth Defects: Original Article Series, Vol 8, No 7 (The National Foundation, New York 1972) Chicago Conference (1966): "Standardization in Human Cytogenetics." Birth Defects: Original Article Series, Vol 2, No 2 (The National Foundation, New York 1966). London Conference (1963): "London Conference on the Normal Human Karyotype." Cytogenetics 2:264–268 (1963) Denver Conference (1960): "A proposed standard system of nomenclature of human mitotic chromosomes." The Lancet 275.7133 (1960): 1063-1065.
See also Locus (genetics) Cytogenetic notation
References
External links About the ISCN recommendations - Human Genome Variation Society