Sophia Horner-Sam (21 July 1949 – 19 September 2026) was a Ghanaian diplomat and politician under President Nana Akuffo-Addo of New Patriotic Party.

Life and career Horner-Sam was born on 21 July 1949.Profile of Sophia Horner-Sam She served as Deputy Western Regional Minister and Deputy Minister of Ports, Harbours and Railways during the John Agyekum Kufour administration. In July 2017, President Nana Akuffo-Addo appointed her as Ghana's ambassador to the Kingdom of Netherlands.

Horner-Sam died on 19 September 2026, at the age of 77.Former NPP Vice Chairperson Sophia Horner-Sam dies at 77

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