Eczematolepis is an extinct genus of ptyctodontidan from the Milwaukee Formation of Wisconsin. Three species are known: E. fragilis, E. pustulosus and E. telleri.Eastman, C. R. 1898 B, p. 55, fig. 49. 1899 B, p. 283. It was originally classified as the genus Acantholepis but that name was preoccupied.

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