The canton of Descartes is an administrative division of the Indre-et-Loire department, central France. Its borders were modified at the French canton reorganisation which came into effect in March 2015. Its seat is in Descartes.

It consists of the following communes:

Abilly Barrou Betz-le-Château Bossay-sur-Claise Bossée Bournan Boussay La Celle-Guenand La Celle-Saint-Avant Chambon La Chapelle-Blanche-Saint-Martin Charnizay Chaumussay Ciran Civray-sur-Esves Cussay Descartes Draché Esves-le-Moutier Ferrière-Larçon Le Grand-Pressigny La Guerche Ligueil Louans Le Louroux Manthelan Marcé-sur-Esves Mouzay Neuilly-le-Brignon Paulmy Le Petit-Pressigny Preuilly-sur-Claise Saint-Flovier Sepmes Tournon-Saint-Pierre Varennes Vou Yzeures-sur-Creuse

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