Driskell is a surname. Notable people with the surname include:
David Driskell (1931–2020), American artist Ethan Driskell (born 2000), American football player Fentrice Driskell (born 1979), American politician Gretchen Driskell (born 1958), American politician James Driskell (born 1959), Canadian man wrongly convicted of murder John Driskell Hopkins (born 1971), American singer, musician, songwriter