Chiappini is an Italian surname. Notable people with the surname include:
Alessandro Chiappini (born 1969), Italian volleyball coach Barbara Chiappini (born 1974), Italian model and actress Izabella Chiappini (born 1995), Brazilian water polo player Maria Stella Wynn, Lady Newborough (née Chiappini; 1773–1843), Italian-born memoirist, Grand Master of Freemasonry, self-styled legitimate daughter of Louis Philippe II Pietro Chiappini (1915–1988), Italian cyclist
See also Chiappa Monte Chiappo, one of the Apennine Mountains in Italy