Sycamore is an unincorporated community in Greene County, Pennsylvania, United States. The community is located along Pennsylvania Route 18, west-northwest of Waynesburg. Sycamore has a post office with ZIP code 15364, which opened on April 25, 1878.
Notable person William J. Ely (1911–2017), United States Army general and writer, was born in Sycamore.Shrum, Rick (September 21, 2017). "Claysville's Bill Ely, West Point class of '33, dies at 105". The Observer-Reporter, Retrieved October 28, 2024.
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