This list of traffic collisions records serious road traffic accidents, with multiple fatalities. The list includes notable accidents with at least 10 deaths, which either occurred in unusual circumstances, or have some other significance. For crashes that killed notable people, refer to the list of people who died in traffic collisions. This list records crashes from the year 2000. For earlier crashes, see list of traffic collisions (before 2000).

Notable traffic collisions 2000s: 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010s: 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020s: 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 References

2000s 2000 January 2 Peru A vehicle fell into a ravine in Tutumbaro, killing 29. January 9 Peru A bus fell into the Mantaro River near La Oroya, killing 29 and injuring 23. January 12 Brazil A tourist bus collided with another bus in Santa Catarina, killing 42 and injuring 40. February 19 Peru A bus fell into the Carhuacayán river in Yauli province, killing 35 and injuring 15. March 2 Peru A bus plunged into a ravine near Ocros District, Huamanga, killing 30. March 29Kenya Two buses collided and overturned near Kericho, killing 74 and injuring 58. July 7SpainA bus collided head-on with a truck near Soria, killing 27 and injuring 13. August 28NigeriaAbuja bus crash. A lorry crushed three buses after its brakes failed, rolling backwards into a crowded bus station, killing over 70. Related riots the next day killed four more. November 5NigeriaIbadan road tanker explosion. A petrol tanker ploughed into a traffic jam and exploded, killing around 200. November 13 Peru A truck overturned on the Puno-Arequipa highway, killing 27. December 25PhilippinesA bus was rear-ended and pushed off a 13-meter embankment by another bus in Bansalan, killing 38.

2001 January 27AustraliaGerogery level crossing accident. A car was struck by an XPT service traveling at , killing five. February 12PeruA bus collided with a truck on the Pan-American Highway near Casma, killing 20. February 16PeruA bus fell into a ravine in Puno Department, killing 20 and injuring 23. February 28United KingdomSelby rail crash. A car was driven off the M62 motorway onto railway tracks, causing the derailment of a passenger train and its subsequent collision with a freight train; the latter killed 10 and injured 82. March 4PortugalHintze Ribeiro Bridge collapse. A bridge across the Douro river collapsed as a bus and three cars were crossing, killing 59. March 16SudanA bus collided with a fuel truck in Kosti, killing 21 and injuring 50. March 19PhilippinesA diesel tanker crashed into five vehicles before catching fire in Parañaque, killing 14 and injuring three. March 19PhilippinesA truck collided with a bus along the North Luzon Expressway in Bocaue, killing 12 and injuring 12. April 1PeruA bus fell from a bridge in Huamanga province, killing 18 and injuring 46. June 25TanzaniaA truck overturned near Sumbawanga, killing 25 and injuring 30. August 1IndiaA jeep collided head-on with a bus in Rajasthan, killing 13 and injuring 15. October 26PhilippinesA bus hit a crowded house in Buenavista, Agusan del Norte, killing 21 and injuring six. November 18Peru A bus plunged off a ravine near Yanahuanca, killing 24 and injuring 19.

2002 February 2PhilippinesA bus plunged off a ravine in Bokod, Benguet, killing 12. February 16PeruA bus overturned on the Ilo-Desaguadero highway, near Mazocruz, killing 22 and injuring 28. March 13PeruA bus overturned after crashing into a gas station in Chincha, Ica Department, killing 33 and injuring 17. April 12IndiaA van carrying Hindu pilgrims crashed into a truck in Calcutta, killing 21 and injuring 17. April 26PhilippinesA jeepney collided with a bus in Bambang, Nueva Vizcaya, killing 11 and injuring six. May 26United StatesI-40 bridge disaster. A barge collided with a bridge support in Oklahoma, causing a section of the bridge to plunge into the Arkansas River, killing 14 and injuring 11. May 27Peru A truck crashed into three houses in Tacna, killing 29 and injuring 11. July 1HungaryA bus carrying Polish pilgrims slid off a road and overturned near Balatonszentgyorgy, killing 19 and injuring 32. August 10PhilippinesA van collided with a speeding truck in Liloy, killing 11 and injuring two. September 2BoliviaA bus carrying more than 45 passengers slid off a road and plunged 170 meters down a ravine near La Paz, killing 25. September 15ArgentinaA bus plunged into a ravine in Catamarca Province, killing 47 and injuring 26. November 6EgyptA tourist bus carrying 50 people slammed into a truck loaded with rocks between Cairo and Sharm el-Sheikh, killing 27 and injuring 24. November 24PhilippinesA bus fell into a creek in Tagkawayan, killing 33 and injuring six.

2003 January 28IndiaA tourist bus collided head-on with a truck in West Bengal, killing 42. April 13 Greece Tempi road accident disaster. An intercity bus carrying 49 students and three accompanying teachers returning from a school trip to Athens collided head-on with a truck in Tempi, killing 21 and injuring 32. April 27PhilippinesA jeep hit an oncoming bus on a mountain road in Tagkawayan, causing the bus to plunge into a ravine, killing 11 and injuring 31. May 1South AfricaSol Plaatje Dam bus crash. A coach drove into the Sol Plaatje Dam at night, killing 51. June 4IndiaKasganj level crossing disaster. A bus was hit by a train on an open level crossing in Kasganj, killing 49 and injuring 29. July 10Hong KongTuen Mun Road bus accident. A bus plunged off a bridge following a collision with a lorry, killing 21. July 16United StatesSanta Monica Farmers Market crash. An elderly man drove into a farmers' market after hitting another car, killing 10 and injuring 70. September 22PhilippinesA bus collided with another bus and a van before plunging into a ravine in Gattaran, killing 14. September 27PhilippinesA minibus hit a waiting shed in Mariveles, killing 14. October 8IndonesiaEast Java bus crash. A truck collided with a bus head-on near Situbondo, then another truck collided with the rear of the bus which caught fire, killing 54. It was the deadliest road accident in Indonesia's history. October 10PeruA bus plunged into the Vizcarra River, killing 40. October 21PakistanA bus skidded off a bridge and fell into a ditch in Abbottabad, killing 20 and injuring 35. November 15PhilippinesA jeepney rammed a truck in Silay, killing 15. December 16PeruA bus fell into a ravine near Cerro de Pasco, killing 27.

2004 January 31PhilippinesTwo buses collided in Botolan, killing 10. March 19FinlandKonginkangas bus disaster. The trailer of a truck swerved into a bus, killing 23 and injuring 14. April 11United KingdomIngoldmells bus crash. A double-decker bus collided with pedestrians in Ingoldmells, killing five. May 4Burkina FasoA fuel truck collided with a bus and caught fire in Niangoloko, killing 35. May 24RomaniaMihăilești explosion. A truck loaded with ammonium nitrate rolled over and caught fire before exploding, killing 18 and injuring 13. June 16PakistanA bus collided with a truck and plunged from the Kak Pul in Islamabad, killing 40 and injuring 10. July 9PeruTwo buses collided on the Pan-American Highway near Palpa District due to thick fog, killing 37. August 1PeruA bus plunged into a ravine in Ancash, killing 32 and injuring 15. August 18IranZahedan bus crash. A bus collided with a truck, killing 15 and injuring 20. October 9United StatesA tour bus plunged off Interstate 55 in Arkansas, killing 15. November 6United KingdomUfton Nervet rail crash. A train hit a car and derailed, killing seven and injuring 71.

2005 January 10IndiaA bus fell into a canal in Bijapur district, Karnataka, killing 51. February 3IndiaNagpur level crossing disaster. A crowded trailer being towed by a tractor was hit by a train, killing 55. April 2PhilippinesA bus collided with a jeepney in San Fabian, Pangasinan, killing 18. April 8ZambiaA truck carrying students overturned while descending a hill in Kawambwa, killing 44. April 27Sri LankaPolgahawela level crossing accident. A bus was hit by train, killing 41. May 7PeruA bus fell off a cliff in Corongo province, killing 40 and injuring 18. May 15VietnamA bus fell down ravine after colliding with a motorcycle in Tam Đường, killing 19. May 21PeruA bus fell into the Mantaro River near Jauja, killing 37 and injuring 24. May 22PhilippinesA bus slammed into a roadside boulder in Tuba, Benguet, killing 27. June 7NepalBadarmude bus explosion. A bus struck a land mine, killing 38. September 30PolandA bus carrying high school students collided with a truck and burst into flames in Białystok, killing 12. October 15PeruA bus fell into the Mantaro River in Izcuchaca, killing 30 . November 24PeruA bus fell into the Rimac River in Huarochirí province, killing 22 and injuring 20.

2006 January 20IndiaAn overcrowded bus plunged into a gorge in Rajouri, killing 52 and injuring 15. February 13PeruA bus crashed into a mountain near Tintay District, killing 28 and injuring 50. February 17CanadaWhite-out conditions caused a 38-vehicle pileup in Embrun, Ontario, killing five. February 18AustraliaCardross road crash. A car hit a group of pedestrians in Cardross, Victoria, killing six. February 27PeruA bus plunged into a ravine in Arequipa Department, killing 26 and injuring 12 March 9TurkeyA bus carrying about 40 people drove off a road and plunged into the Kelkit River in Tokat Province, killing 16 and injuring 11. April 17MexicoA bus crashed about down a ravine and into a stream in Veracruz, killing 57. May 11PhilippinesA van collided with a bus in Panabo, killing 11. June 23EgyptSinai bus crash. A bus overturned and landed upside down between Nuweiba and Taba, killing 12. July 5KazakhstanA bus collided with a truck in Shetskiy district, killing 15. September 30CanadaDe la Concorde overpass collapse. A section of a 3-lane overpass over Autoroute 19 collapsed, killing five and injuring six. October 26PeruA bus plunged into a ravine in Vitor District, killing 24. October 28PhilippinesA dump truck lost its brakes at a downhill curve and crashed into several vehicles and villagers celebrating a religious feast in Makilala, killing 18. November 13South AfricaFaure level crossing accident. A truck carrying workers was hit by a train, killing 19 and injuring six. December 5PeruA bus traveling plunged into a ravine near Ollachea, killing 45. December 13PeruA truck and a bus collided in Bagua province, killing 26.

2007 January 6BangladeshComilla bus crash. A bus crashed and caught fire, killing 65. January 25 – Mexico – A bus fell off a ravine near Huautla de Jiménez, killing 33. February 2PhilippinesA burning chemical truck exploded as a bus was passing beside it in Tigbao, Zamboanga del Sur, killing 50. May 11IndiaA bus skidded off a bridge and fell into the Ganges river in Bihar, killing 20. May 11IndiaA jeep collided with an oil tanker in Mayurbhanj, killing 11 and injuring four. June 5AustraliaKerang train accident. A train collided with a truck at the junction of the Murray Valley Highway and the Piangil railway line near Kerang, killing 11. July 1PeruA bus collided with a truck on the Pan-American Highway in La Libertad Department, killing 24. July 17Republic of the CongoA packed truck overturned near Pointe-Noire, killing 18. July 22PhilippinesA truck collided with a motorcycle in Calbayog, killing 13 and injuring 30. July 22FranceRampe de Laffrey accident. A bus drove off the road and into a ravine near Vizille, killing 26 and injuring 24. August 1United StatesI-35W Mississippi River Bridge collapse. The structure and deck of a bridge collapsed into the Mississippi River and onto the riverbanks, killing 13. August 13MalaysiaA bus crashed into a ditch on the North–South Expressway in Bukit Gantang, killing 20. October 16PeruA bus plunged into a ravine near La Oroya, killing 22.