Darmanin is a surname. Notable people include:

Edward Darmanin (born 1945), Maltese footballer Gérald Darmanin, (born 1982) French politician, Minister of the Interior Lisa Darmanin (politician), Australian politician Lisa Darmanin (sailor) (born 1991), Australian sailor Paul Darmanin (born 1940), Maltese catholic prelate; Bishop of Garissa, Kenya Saviour Darmanin (born 1977), Maltese footballer