Bis-GMA (bisphenol A-glycidyl methacrylate) is a resin commonly used in dental composite, dental sealants, and dental cement.. Retrieved 27 May 2022. It is a diester derived from methacrylic acid and bisphenol A diglycidyl ether. Bearing two polymerizable groups, it is prone to form a crosslinked polymer that is used in dental restorations. For dental work, highly viscous bis-GMA is mixed with aluminosilicate particles, crushed quartz, and other related acrylates; changes to component ratios result in different physical properties in the end product. Bis-GMA was first incorporated into composite dental resins in 1962 by Rafael Bowen. Until matrix development work in the early 2000s, bis-GMA and related methacrylate monomers were the only options for organic matrix composition.
Safety Concerns have been raised about the potential for bis-GMA to break down into or be contaminated with the related compound bisphenol A. However, no negative health effects of bis-GMA use in dental resins have been found.
Composition Salivary esterases can slowly degrade bis-GMA-based sealants, forming bis-HPPP.
References
Further reading