Malian football clubs have participated in African football competitions since 1965. In total, Malian clubs have participated in African competitions. The biggest success was the participation of Stade Malien in the finals at the 2009 CAF Confederation Cup and Stade Malien and became the only Malian club to win a continental cup title, later Stade Malien was the only Malian club who appeared in the CAF Super Cup in 2010 where they lost the title to Democratic Congo's TP Mazembe.
Of the continental appearances, Djoliba and Stade Malien are one of the African clubs who appeared the most at continental competitions.
Appearances in CAF competitions As of March 2017 CAF Champions LeagueCAF Confederation CupCAF Cup Winners' CupCAF CupTotalclubAppMatWDL AppMatWDL AppMatWDL AppMatWDL AppMatWDL Djoliba ACLe Djoliba s’adjuge la Super Coupe du Mali de football . APA News, 7 December 2008.1976105341661733145Stade Malien2277251834143813141372063111201144137443658Real Bamako830137104000001240CO Bamako1210100000622USFAS Bamako0000031033424121514455Centre Salif KeitaOnze CreateursAS Nianan00000120111410314211310325AS Bamako0000016321000000000016321AS Sigui0000012020000001410326123AS Bakaridjan0000012020000000000012020Mamahira AC0000012002000000000012002
African Cup of Champions Clubs/CAF Champions League Season Club Round Opponent Home Away Aggregate1964–65Stade MalienFirst Round Espoir de Saint-Louis4–11–1Second Round Sily Club de Kindia2–02–4Quarterfinals ASEC Mimosas3–36–4Semifinals Cotton Factory Club3–1Finals Oryx Douala1–21966Real BamakoFirst Round Invincible Eleven6–02–3Quarterfinals AS Kaloum Star2–12–3Semifinals Stade d'Abidjan3–14–1 (aet)Finals Wydad Casablanca2–13–11967Djoliba ACSecond Round Invincible Elevenw/oQuarterfinals Hafia FC2–10–0Semifinals Hearts of Oak1–12–11970Real BamakoFirst Round AS Fonctionnaires3–02–2Second Round Stade d'Abidjan2–36–21971Stade MalienFirst Round ASC Diaraf4–00–3Second Round ASEC Mimosas2–21–21972Djoliba ACFirst Round ASFA Ouagadougou1–01–3Second Round ASFA Dakar2–02–01Quarterfinals Hafia FC2–13–01973Stade MalienFirst Round Modèle de Lomé2–10–0Second RoundAS Vita Club0–31–41974Djoliba ACSecond Round Bendel Insurance2–01–0QuarterfinalsCARA Brazzaville0–03–01975Djoliba ACFirst Round Mighty Blackpool2–00–1Second Round Lomé1–13–21976Djoliba ACFirst Round Real de Banjul2–00–2 (a)Second Round Hafia FC2–12–01977Djoliba ACFirst Round UDI Bissau5–00–1Second Round SC Gagnoa1–11–3Semifinals Lomé2–01–021980Djoliba ACFirst Round AS Niamey2–00–1Second Round Hearts of Oak1–11–01981Real BamakoFirst Round US Mbila Nzambi1–01–0 (2–4 p)1982Real BamakoFirst RoundÉtoile du Congo1–01–1Second Round USM Libreville2–01–0QuarterfinalsSaint Éloi Lupopo3–22–01983Djoliba ACPreliminary Round Hafia FC0–01–01984Real BamakoFirst RoundDragons FC de l'Ouémé2–22–01985Stade MalienSecond Round Invincible Eleven1–10–33Quarterfinals GCR Mascara2–03–01987Real BamakoFirst Round Leventis United0–04–01988Stade MalienFirst Round ES Sétif1–10–41989Djoliba ACFirst Round Horoya AC1–00–0Second Round Mighty Blackpool0–01–21990Stade MalienFirst Round Espérance Tunis0–10–21991Djoliba ACFirst Round ASC Port Autonome1–00–0Second Round Club Africain0–02–01992Real BamakoPreliminary Round ASC Police1–11–1 (5–4 p)First Round WAC Casablanca2–12–01993Djoliba ACSecond Round Sonader Ksar1–01–1Quarterfinals ASEC Mimosas1–12–01994Stade MalienFirst Round East End Lions2–02–0 (2–3 p)Second Round Espérance Tunis0–13–01995Stade MalienFirst Round Horoya AC1–01–1Second Round Goldfields Obuasi0–00–11997Djoliba ACFirst Round Club Africain1–13–21998Djoliba ACFirst Round Hearts of Oak0–01–01999Djoliba ACFirst Round Cotonsport Garoua2–03–1 (a)Second Round Raja Casablanca2–12–1 (2–4 p)2000Djoliba ACFirst Round Cotonsport Garoua2–03–1 (a)Second Round Raja Casablanca2–12–1 (2–4 p)2001Stade MalienFirst Round ASEC Mimosas2–00–22002Stade MalienFirst Round Hearts of Oak3–11–1Second Round Jeanne d'Arc (Dakar)0–31–22003Stade MalienFirst Round AS Police (Pointe-Noire)1–02–1Second Round USM Alger1–12–02004Stade MalienPreliminary Round Hearts of Oak0–00–22005Djoliba ACPreliminary Round ASC Diaraf1–11–02006Stade MalienFirst Round Satellite FC3–02–2Second Round Renacimiento FC2–11–0 (a)2007Stade MalienFirst Round AS Douanes (Dakar)1–22–0Second Round Wydad Casablanca0–03–12008Stade MalienPreliminary Round Primeiro de Agosto1–20–02010Djoliba ACPreliminary Roundal-Ahly Benghazi1–00–0First Round ASC Linguère1–01–0 (4–3 p)Second Round TP Mazembe0–13–02011Djoliba ACPreliminary Round East End Lions2–00–2First Round ASC Diaraf1–13–0Stade MalienFirst Round Raja Casablanca2–11–0 (a)2012Djoliba ACPreliminary Round URA SC2–00–2First Round Sunshine Stars1–11–0Stade MalienFirst Round Tonnerre5–20–0Second Round al Ahly (Cairo)1–01–32013Stade MalienFirst Round Casa Sports2–02–1Second Round Coton Sport0–00–32014Stade MalienPreliminary Round Sporting Praia Cruz5–03–2First Round Al-Hilal Club0–02–0AS Real BamakoPreliminary Round FAR Rabat1–12–23–3 (a)First Round Enyimba0–11–22–2 (a)Second Round Espérance de Tunis1–13–01–42015CO BamakoPreliminary Round Moghreb Tetouan2–03–02–3Stade MalienPreliminary Round AS GNN0–01–1 (a)1–1 (a)First Round AS Mangasport2–11–35–2Second Round TP Mazembe2–22–13–42016Onze CréateursPreliminary Round al-Ahly Tripoli1–20–01–2Stade MalienPreliminary Round RC Bobo Dioulasso3–10–14–1First Round Cotonsport Garoua2–01–02–1Second Round ZESCO United1–31–22–52017Real BamakoPreliminary Round Rivers United0–00–40–4Stade MalienFirst Round Barrack Young Controllers FC1–00–1 (6–7 p)1–1p2018Stade MalienPreliminary Round Williamsville AC1–10–11–2Real BamakoPreliminary Round MFM F.C.1–10–11–22018-19Stade MalienPreliminary Round Stade Centrafricaine4–01–05–0First Round ASEC Mimosas0–10–10–22019-20Stade MalienPreliminary Round Horoya AC1–10–11–22020-21Stade MalienPreliminary Round AS Ashanti Golden Boys2–0 (awd.)2–14–1First Round Wydad AC1–00–31–3 2021-22Stade MalienFirst Round AS SONABEL3–01–04–0Second Round Horoya AC1–00–31–3 2022-23Djoliba ACFirst Round Deportivo Mongomo5–00–25–2Second Round CR Belouizdad2–10–22–3 2023-24Real BamakoFirst Round Coton Sport0–02–02–0Second Round FC Nouadhibou0–31–11–4 2024-25Djoliba ACFirst Round Red Star de Bangui0–0—w/oSecond Round ASKO Kara1–01–02–0 Group stage:4th place Espérance Sportive de Tunis0–10–4 Pyramids0–00–6 Sagrada Esperança0–00–12025-26Stade MalienFirst Round AS Tempête2–05–07–0Second Round FC Nouadhibou2–01–13–1 Group stage:1st place Espérance Sportive de Tunis1–00–0 Petróleos de Luanda2–00–0 Simba2–10–1Quarter-finals Mamelodi Sundowns2–00–32–3
African (CAF) Cup Winner's Cup/CAF Confederation Cup