Dafna (), is a feminine given name. Notable people with the given name include:
Dafna Bar-Sagi an Israeli-American cell biologist and cancer researcher Dafna Dekel, Israeli singer and actress Dafna D. Gladman, a Canadian doctor and medical researcher Dafna Kaffeman, Israeli artist Dafna Lemish, Israeli-American media researcher Dafna Linzer, journalist Dafna Michaelson Jenet, an Israeli-American politician Dafna Rechter, Israeli actress and singer