Sámano is a surname. Notable persons with this name include: Érick Sámano (born 1991), Mexican footballer Eva Sámano (1910–1984), Mexican educator and first lady of Mexico Juan José de Sámano y Uribarri (1753–1821), Spanish soldier Miguel Sámano Peralta (born 1966), Mexican politician Jeanette Sámano, actress Lupe Sámano, patient on My 600-lb Life Samano, a city in Cantabria, Spain