Karls may refer to:
Surname Karen Karls, American politician Ken Karls (born 1947), Chairman of the North Dakota Republican Party 2003–2007 Tommy Karls (born 1961), Swedish sprint and marathon canoeist
Other Karls robber frog (Eleutherodactylus karlschmidti), a possibly extinct Puerto Rican frog species Kong Karls Land, island group in the Svalbard archipelago, in the Arctic Ocean
See also KARL Karl (disambiguation) Karlsen (disambiguation) Karlson (disambiguation)