Kilonzo is a surname. Notable people with the surname include:
Charles Kilonzo, Kenyan politician Cleopa Kilonzo Mailu (born c. 1956), Kenyan politician Kakai Kilonzo (born 1954), Kenyan musician Kethi Kilonzo (born 1977), Kenyan lawyer Kiema Kilonzo, Kenyan politician Mutula Kilonzo (1948-2013), Kenyan politician Nduku Kilonzo (born 1974), Kenyan businesswoman Stella Kilonzo (born 1975), Kenyan businesswoman