The Clifford-Wyrick House is a historic house located at 105 South Second Street in Clarksville, Pike County, Missouri.
Description and history It was constructed in 1878, and is a one-story, irregularly-shaped, vernacular Italianate style frame dwelling. It is sheathed in clapboard siding. It features a two-bay porch across the south part of the facade and projecting gabled bays. (includes 7 photographs from 1983)
It was listed on the National Register of Historic Places on July 9, 1984. It is located in the Clarksville Historic District.
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