Region 3 or Region III may refer to:

Government Region 3, Northwest Territories, a Statistics Canada census division Former Region 3 (Johannesburg), an administrative district in the city of Johannesburg, South Africa, from 2000 to 2006 Central Luzon (designated as Region II), an administrative region in the Philippines One of Regions of Iran, commonly known as Azerbaijan (Iran)

Technology DVD region 3, one of the DVD regions ITU Region 3, consisting of the Americas