The Mandalay Region Government is responsible for leading the Mandalay Region. The cabinet is led by chief minister Maung Ko.

Cabinet (2021 - current) NoName Term of serviceMinistryTook officeLeft officeDays1Maung Ko1 August 2021IncumbentChief Minister2Col Kyaw Kyaw Min1 August 2021IncumbentMinistry of Security and Border Affairs3Thein Htay1 August 2021IncumbentMinistry of Commerce4Myo Aung1 August 2021IncumbentMinistry of Natural Resources5Yin Htwe1 August 2021IncumbentMinistry of Social Affairs6Police Brigadier General Sein Lwin1 August 2021IncumbentMinistry of Roads and Communication7Sai Nwam1 August 2021IncumbentMinistry of Ethnic Affairs8Kyaw San1 August 2021IncumbentMinistry of Municipal9Region Advocate

Cabinet (2016–2021) NoName Term of serviceMinistryTook officeLeft officeDays1Zaw Myint Maung30 March 20161 February 2021 Chief Minister2Col Myo Min Aung5 April 20166 July 2017 Ministry of Security and Border AffairsCol Kyaw Kyaw Min6 July 20171 February 2021 3Soe Than5 April 20161 February 2021 Ministry of Agriculture, Livestock and Irrigation4Zarni Aung5 April 20161 February 2021 Ministry of Electricity, Energy and Construction5Myo Thit5 April 20161 February 2021 Ministry of Natural Resource and Environment6Myat Thu5 April 20161 February 2021 Ministry of Planning and Finance7Ye Lwin5 April 20161 February 2021 Ministry of Municipal8Sai Kyaw Zaw30 March 201616 January 2018Ministry of Shan Ethnic AffairsSai Parn Seng18 December 20181 February 2021 9Aung Win7 April 2016 - -Region Advocate10Khin Aye Swe7 April 2016 - -Region Auditor

Cabinet(2011-2016) No Name Ministry(1)Ye MyintChief Minister(2)Col Aung Kyaw MoeMinistry of Security and Border Affairs(3)Myint KyuMinistry of Finance(4)Myint ThanMinistry of Agriculture and Livestock Breeding(5)Than Soe MyintMinistry of Forestry and Mines(6)Aung ZanMinistry of Planning and Economics(7)Kyaw HsanMinistry of Transport(8)Kyaw MyintMinistry of Electric Power and Industry(9)Aung MaungMinistry of Development Affairs(10)Win HlaingMinistry of Social Affairs(11)Maung HlaMinistry of National Races Affairs The former Development Affairs minister is Phone Zaw Han who was replaced with Aung Maung.

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