This is a list of mayors of Cape Breton Regional Municipality, Nova Scotia, Canada. The region's first mayor John Coady was elected in 1995 when the region was created by the province through amalgamation of the previous municipal units.

List # Mayor Term start Term end Notes 1 John Coady 1 August 1995 20 October 1997 Previously Warden for Cape Breton County 2 David Muise (born 1949) 20 October 1997 20 October 2000 Previously MLA for Cape Breton West 3 John W. Morgan (born 1964) 20 October 2000 20 October 2012 4 Cecil Clarke (born 1964) 20 October 2012 4 November 2020 Previously MLA for Cape Breton North 5 Amanda McDougall 5 November 2020 30 October 2024 Previously a regional councillor – Cecil Clarke 30 October 2024 Previously mayor (2012–2020)

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