109 may refer to:

109 (number), the natural number following 108 and preceding 110 AD 109, a year of the Julian calendar, in the second century AD 109 BC, a year of the pre-Julian Roman calendar 109 (department store), a department store in Shibuya, Tokyo, Japan Route 109 (MBTA), a bus route in Massachusetts, US Messerschmitt Bf 109, a German World War II fighter plane M109 howitzer, an American self-propelled howitzer 109 Felicitas, a main-belt asteroid

See also 10/9 (disambiguation) Meitnerium, synthetic chemical element with atomic number 109