Reason is an English surname. It originates as a nickname for "a man of reason, good judgement, or wise words" and the word ultimately comes from Old French raisun, raiso(u)n.

Notable people with the surname include: Charles L. Reason (1818–1893), American linguist and mathematician Dana Reason, 20th/21st-century Canadian musician J. Paul Reason (born 1941), American naval officer James Reason (1938–2025), British psychology professor John Reason, possible alternative name of Reasonable Blackman Jumbo Reason (1884–?), English footballer Patrick H. Reason (1816–1898), American lithographer and engraver

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