Blair Hollow is a valley in Ozark County in the Ozarks of south central Missouri. The valley is a tributary to North Fork River. The head of the valley lies just northwest of U.S. Route 160.Bakersfield, Missouri, 7.5 Minute Topographic Quadrangle, U.S. Geological Survey, 1968 Tecumseh is about three miles to the southwest along the North Fork.Missouri Atlas & Gazetteer, DeLorme, 1998, First edition, p. 64,

The headwaters of the stream in the valley are at and the confluence with the North Fork River are at .

Blair Hollow has the name of the local Blair family.

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