John Ebersole may refer to:
John H. Ebersole (1925–1993), American pioneer in submarine medicine and radiation oncology, Captain US Navy John Ebersole (American football) (born 1948), American former National Football League player John Ebersole (educator) (1944–2016), American educator, author and columnist
See also John T. Eversole (1915–1942), U.S. Navy officer